Category: The ScienceScience and medical journal publications or articles and videos of reputable people using cited sources.
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Science and medical journal publications or articles and videos of reputable people using cited sources.
We search and collate these for you into a more digestible form in simply described categories.
If you wish to read more simplified or interpreted information, check our articles out in the Resources menu.
Autistic People Care Too Much, Research Says » NeuroClastic
Autistic people don’t care too much, they care correctly. Many autistic people have immense integrity. It’s okay to acknowledge that. In fact, it’s imperative that we acknowledge that.
https://neuroclastic.com/autistic-people-care-too-much-research-says/?amp
The Smiles Trial: Nutrition for Depression | Ideal Nutrition
Each food, beverage, or mixed dish receives a final Food Compass score ranging from 1 (least healthy) to 100 (most healthy). The researchers identified 70 or more as a reasonable score for foods or beverages that should be encouraged. Foods and beverages scoring 31-69 should be consumed in moderation. Anything scoring 30 or lower should be consumed minimally.
Across major food categories, the average Food Compass score was 43.2.
The lowest scoring category was snacks and sweet desserts (average score 16.4).
The highest scoring categories were vegetables (average score 69.1), fruits (average score 73.9, with nearly all raw fruits receiving a score of 100), and legumes, nuts, and seeds (average score 78.6).
Among beverages, the average score ranged from 27.6 for sugar-sweetened sodas and energy drinks to 67 for 100% fruit or vegetable juices.
Starchy vegetables scored an average of 43.2.
The average score for beef was 24.9; for poultry, 42.67; and for seafood, 67.0.
Fasting and Exercise Induce Changes in Serum Vitamin D Metabolites in Healthy Men
Increases in 24,25(OH)2D3 and 3-epi-25(OH)D3 levels imply that fasting stimulates vitamin D metabolism. The effects of exercise on serum vitamin D metabolites, which are most pronounced after fasting and in subjects with serum 25(OH)D3 above 25 ng/mL, support the notion that fasting and exercise augment vitamin D metabolism.
Frontiers | The Effects of Daytime Psilocybin Administration on Sleep: Implications for Antidepressant Action | Pharmacology
Psilocybin (O-phosphoryl-4hydroxy-N, N-dimethyltryptamine) and its active metabolite psilocin (4-hydroxy-N, N-dimethyltryptamine) are the main psychoactive components of psychedelic mushrooms. In the central nervous system, psilocin acts as an agonist of serotonergic 5-HT1A and 5-HT2A/C receptors, leading to altered states of consciousness in humans (Tyls et al., 2014). Psilocybin doses of 0.04–0.43 mg/kg cause alterations in perception, cognition, and emotions, while also eliciting long-term changes in well-being and mood in both healthy and psychiatric subjects (Dos Santos et al., 2016; Kor?ák et al., 2019; Barrett et al., 2020). These long-lasting positive changes lead to an exploration of the therapeutic potential of psychedelics as well as the mechanisms underlying this potential. Because of its general safety, intermediate duration of action, and therapeutic potential in several neuropsychiatric disorders, psilocybin is currently the most intensely studied psychedelic in clinical trials (Sewell et al., 2006; Grob et al., 2011; Stebelska, 2013; Dos Santos, 2014).
Overall, there has been an increasing preclinical (Catlow et al., 2013; Baumeister et al., 2014) and clinical (Carhart-Harris et al., 2016; Bogenschutz and Ross, 2018) evidence for the antidepressant potential of psilocybin. Although exact mechanisms are currently unknown, it is generally believed to be attributed to either a direct action on 5-HT receptors or the psychological effects of acute intoxication (Carhart-Harris and Goodwin, 2017). It has been shown that serotonergic psychedelics including psilocybin via 5-HT2A receptors promote neuroplasticity (Ly et al., 2018), a fundamental mechanism of neuronal adaptation that is disrupted in depression (Carhart-Harris and Goodwin, 2017) and restored by antidepressant treatments including selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs) or electroconvulsive therapy (ECT) (Hayley and Littlejohn, 2013).
https://www.frontiersin.org/articles/10.3389/fphar.2020.602590/full
Nutrients | Free Full-Text | Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial
Our findings suggest that L-theanine has the potential to promote mental health in the general population with stress-related ailments and cognitive impairments.
BrainNet: A Multi-Person Brain-to-Brain Interface for Direct Collaboration Between Brains
We present BrainNet which, to our knowledge, is the first multi-person non-invasive direct brain-to-brain interface for collaborative problem solving. The interface combines electroencephalography (EEG) to record brain signals and transcranial magnetic stimulation (TMS) to deliver information noninvasively to the brain.
Research News – Success in Reversing Dementia in Mice Sets the Stage for Human Clinical Trials | Tohoku University Global Site
Researchers have identified a new treatment candidate that appears to not only halt neurodegenerative symptoms in mouse models of dementia and Alzheimer’s disease, but also reverse the effects of the disorders.
https://www.tohoku.ac.jp/en/press/eversing_dementia_stage_set_for_human_clinical_trials.html
The terrible science behind popular weight loss products
Dietary supplements and alternative therapies for weight loss have a limited high-quality evidence base of efficacy. Practitioners and patients should be aware of the scientific evidence of claims before recommending use.
https://www.inverse.com/mind-body/new-study-debunks-weight-loss-supplements
Running to music combats mental fatigue, study suggests — ScienceDaily
Listening to music while running might be the key to improving people’s performance when they feel mentally fatigued a study suggests. The performance of runners who listened to a self-selected playlist after completing a demanding thinking task was at the same level as when they were not mentally fatigued, the research found. The study is the first to investigate the effect of listening to music playlists on endurance running capacity and performance when mentally fatigued.
https://www.sciencedaily.com/releases/2021/06/210622123235.htm
Western high-fat diet can cause chronic pain, according to new study — ScienceDaily
In the new paper, Dr. Boyd and his colleagues used multiple methods in both mice and humans to study the role of polyunsaturated fatty acids in pain conditions. They found that typical Western diets high in omega-6 polyunsaturated fats served as a significant risk factor for both inflammatory and neuropathic pain.
https://www.sciencedaily.com/releases/2021/06/210623141644.htm
Evidence for Clinical Use of Honey in Wound Healing as an Anti-bacterial, Anti-inflammatory Anti-oxidant and Anti-viral Agent: A Review
Honey has almost equal or slightly superior effects when compared with conventional treatments for acute wounds and superficial partial thickness burns.
Study: Men doing more family caregiving could lower their risk of suicide | EurekAlert! Science News
Men’s family caregiving, unemployment, and suicide
The multinational and multidisciplinary study, published in Social Psychiatry and Psychiatric Epidemiology by Canetto, Ying-Yeh Chen, ZiYi Cai, Qingsong Chang, and Paul Yip, offers evidence of a suicide-protective role for men who engage in family caregiving. In their study, family caregiving was defined as, for example, providing personal care or education for a child, and/or providing care for a dependent adult.
The researchers examined suicide, male family caregiving, and unemployment in 20 countries, including the United States, Austria, Belgium, Canada and Japan. Suicide rates were found to be lower in countries where men reported more family care work.
In countries where men reported more such care work, higher unemployment rates were not associated with higher suicide rates in men. By contrast, in countries where men reported less family care work, higher unemployment rates were associated with elevated male suicide rates. Incidentally, unemployment benefits did not reduce male suicide rates.
Taken together, the findings of this ecological study suggest that men’s family care work may protect them against suicide, particularly under difficult economic circumstances, Canetto said.
https://www.eurekalert.org/pub_releases/2021-06/csu-smd061821.php
A catalog of tens of thousands of viruses from human metagenomes reveals hidden associations with chronic diseases | PNAS
The microbiome, an important regulator of metabolic and immune-related phenotypes, has been shown to be associated with or participate in the development of a variety of chronic diseases. Viruses of bacteria (i.e., “phages”) are ubiquitous and mysterious, and several studies have shown that phages exert great control over the behavior—and misbehavior—of their host bacteria.
View of Hair Regrowth with Cannabidiol (CBD)-rich Hemp Extract
Androgenetic alopecia (AGA) is the most common cause of hair loss. Several FDA approved medications are available
but offer limited results. Studies have shown that the endocannabinoid system (ECS) is a key player in hair follicle
cell growth. The ECS can
nabinoid type one (CB1) receptors are well expressed in the hair follicle cells. Cannabidiol
CBD is a negative allosteric modulator of the CB1 receptor and has been shown to result in hair shaft elongation. In
addition, the hair follicle cycle phases are c
ontrolled by the ECS vanilloid receptor
–
1 (TRPV1). CBD has also been
shown to increase Wnt signaling pathways that are involved in the differentiation of dermal progenitor cells into new
hair follicles and maintaining the anagen phase of the hair cycle. Th
e effects of CBD on hair growth are dose
dependent and higher doses may result in premature entry into the catagen phase via a receptor known as vanilloid
receptor
–
4 (TRPV4). Topical application of CBD reaches hair follicles where it is a CB1 negative modu
lator, and
TRPV1, and TRPV4 agonist. A study was done of 35 subjects with AGA using a once daily topical hemp oil
formulation, averaging about 3
–
4 mg per day of CBD and minimal amounts of other cannabinoids for six months. A
hair count of the greatest area
of alopecia was carried out before treatment and again after six months. The results
revealed that men did slightly better than women, and the vertex area did better than the temporal areas. On
average there was statistically significant 93.5% increase in
hair after 6 months. All subjects had some regrowth.
There were no reported adverse effects. Since the CBD works through novel mechanisms different from finasteride
and minoxidil it can be used in conjunction with these current drugs and would be expected
to have synergistic
effects.
https://publications.sciences.ucf.edu/cannabis/index.php/Cannabis/article/view/78/47
There Is No Evidence That Associations Between Adolescents’ Digital Technology Engagement and Mental Health Problems Have Increased – Matti Vuorre, Amy Orben, Andrew K. Przybylski, 2021
And this was a warning to regulators and lawmakers focusing on commonly held beliefs about the harmful effects of technology on young people’s mental health.
https://journals.sagepub.com/doi/full/10.1177/2167702621994549
Pain receptors linked to the generation of energy-burning brown fat cells: Vascular smooth muscle-derived Trpv1+ progenitors have found to be a source of cold-induced — ScienceDaily
A new source of energy expending brown fat cells has been uncovered by researchers at the Joslin Diabetes Center, which they say points towards potential new therapeutic options for obesity. According to the new report, published in Nature Metabolism on 12 March 2021, the key lies in the expression of a receptor called Trpv1 (temperature-sensitive ion channel transient receptor potential cation subfamily V member 1) — a protein known to sense noxious stimuli, including pain and temperature.
https://www.sciencedaily.com/releases/2021/04/210412114837.htm
COVID-19 pandemic has been linked with six unhealthy eating behaviors: Study shows a slight increase in eating disorders, one of the deadliest psychiatric health concerns — ScienceDaily
Eat healthy:
A new probe into the lingering impacts of the COVID-19 pandemic revealed correlations to six unhealthy eating behaviors, according to a study by the University of Minnesota Medical School and School of Public Health. Researchers say the most concerning finding indicates a slight increase or the re-emergence of eating disorders, which kill roughly 10,200 people every year — about one person every 52 minutes.
https://www.sciencedaily.com/releases/2021/04/210412114740.htm
CBD reduces plaque, improves cognition in model of familial Alzheimer’s – Jagwire
The investigators report for the first time that CBD normalizes levels and function, improving cognition as it also reduces levels of the immune protein IL-6, which is associated with the high inflammation levels found in Alzheimer’s, says Dr. Babak Baban, immunologist and associate dean for research in the Dental College of Georgia and the study’s corresponding author.
https://jagwire.augusta.edu/cbd-reduces-plaque-improves-cognition-in-model-of-familial-alzheimers/
Study compares low-fat, plant-based diet to low-carb, animal-based diet
People on a low-fat, plant-based diet ate fewer daily calories but had higher insulin and blood glucose levels, compared to when they ate a low-carbohydrate, animal-based diet, according to a small but highly controlled study. The study compared the effects of the two diets on calorie intake, hormone levels, body weight, and more.
https://www.sciencedaily.com/releases/2021/01/210121131851.htm
Brain imaging reveals ADHD as a collection of different disorders — ScienceDaily
Researchers have found that patients with different types of attention-deficit/hyperactivity disorder (ADHD) have impairments in unique brain systems, indicating that there may not be a one-size-fits-all explanation for the cause of the disorder. Based on performance on behavioral tests, adolescents with ADHD fit into one of three subgroups, where each group demonstrated distinct impairments in the brain with no common abnormalities between them.
https://www.sciencedaily.com/releases/2017/11/171107140834.htm
Exercising one arm has twice the benefits — ScienceDaily
New research has revealed that training one arm can improve strength and decrease muscle loss in the other arm — without even moving it. The findings could help to address the muscle wastage and loss of strength often experienced in an immobilized arm, such as after injury, by using eccentric exercise on the opposing arm.
https://www.sciencedaily.com/releases/2020/10/201022112555.htm
Study probes connection between diet quality and environmental sustainability | William & Mary
While a plant based diet may seem to have good environmental credentials, it isn’t necessarily better for the environment.
A plant based diet is also deficient and requires close attention and supplementation.
Exercise and nutrition regimen benefits physical, cognitive health: 12-week double-blind control trial in 148 Air Force airmen — ScienceDaily
“Researchers studied the effects of a 12-week exercise regimen on 148 active-duty Air Force airmen, half of whom also received a twice-daily nutrient beverage that included protein; the omega-3 fatty acid, DHA; lutein; phospholipids; vitamin D; B vitamins and other micronutrients; along with a muscle-promoting compound known as HMB. Both groups improved in physical and cognitive function, with added gains among those who regularly consumed the nutritional beverage, the team reports.”
https://www.sciencedaily.com/releases/2020/10/201019103508.htm
Health and disease markers correlate with gut microbiome composition across thousands of people | Nature Communications
“We identify major axes of taxonomic variance in the gut and a putative diversity maximum along the Firmicutes-to-Bacteroidetes axis. Our analyses reveal both known and unknown associations between microbiome composition and host clinical markers and lifestyle factors, including host-microbe associations that are composition-specific. These results suggest potential opportunities for targeted interventions that alter the composition of the microbiome to improve host health.”
TREATMENT OF AGE-RELATED AND MITOCHONDRIAL DISEASES BY INHIBITION OF HIF-1 ALPHA FUNCTION – President and Fellows of Harvard College
Following we have a new patent application from Dr. David Sinclair et al
It describes the use of NMN on humans and dosage rates.