Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state: Developmental Cell

Health Hacker Australia > The Science > Hair > Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state: Developmental Cell
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Highlights
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Hedgehog signaling in murine fibroblasts induces new hair growth and hair multiplication
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Hedgehog activation increases fibroblast heterogeneity and drives new cell states
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TGF-? pathway downstream of dermal Hedgehog mediates hair growth hyper-activation
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SCUBE3 is a new mesenchymal niche factor that activates hair growth

https://www.cell.com/developmental-cell/fulltext/S1534-5807(22)00414-2?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1534580722004142%3Fshowall%3Dtrue

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