“We recently synthesized a pyrazole derivative of curcumin called CNB-001 that enhances the activity of Ca2+/calmodulin dependent protein kinase II (CaMKII). Since CaMKII plays a central role in long-term potentiation (LTP) and memory, it was asked if CNB-001 can facilitate the induction of LTP in rat hippocampal slices and enhance memory in a rat object recognition test. It is shown that CNB-001 enhances both LTP and memory”

https://www.mendeley.com/catalogue/pyrazole-derivative-curcumin-enhances-memory/