Human life extenssion via Telomerase activation and elongation of Telomeres
Epitalon is one of the very few substances which are able to activate Telomerase (telomere terminal transferase) enzyme in humans. Telomerase renews (elongates) the telomeres, which are responsible for protection of the human DNA from damage and cancer causing errors.
Treatment of aging cells in culture with Epithalon induced elongation of telomeres to the size comparable to their length during the early cell divisions. Epitalon treated cells with elongated telomeres made 10 extra divisions (44 passages) in comparison with the control and continued dividing. Thus, Epithalon prolonged the vital cycle of normal human cells due to overcoming the Heyflick cell division limit. (reference: V. Khavinson et all. in Bulletin of Experimental Biology and Medicine. June 2003, PMID: 12937682)
Epitalon used for Anti Aging
Epitalon decreases the age-related changes in immune and neuroendocrine systems, reduces the incidence of recurrent infections and chronic diseases. Long term clinical trials have shown that in patients with age-related pathology Epithalamin eliminates imbalance in prooxidation and antioxidation systems. (reference: N. Anisimov et all. Neuroendocrinology Letters, 2011, PMID: 11335874)