NAD+ Restoration Therapy

Risk-Benefit Analysis

Forever Healthy Foundation gGmbH

Amalienbadstraße 41

D-76227 Karlsruhe, Germany

NAD+ is a pyridine nucleotide found in all living cells. It plays an important role in energy metabolism and is a substrate for several enzymes (including those involved in DNA repair). NAD+ levels may decline markedly with age (Massudi et al., 2012Clement et al., 2019Zhu et al., 2011) and restoring those levels to a youthful state is believed to have beneficial effects on health and longevity. 

Key Questions 

This analysis seeks to answer the following questions:

  • Which health and/or longevity benefits result from raising NAD+ levels in humans? 
  • Which risks are involved in raising NAD+ levels (general and method-specific)?
  • What are the potential risk mitigation strategies?
  • Which method or combination of methods is most effective in raising NAD+ levels?
  • Which of the available methods are safe for use? 
  • What is the best therapeutic protocol available at the moment?

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