Age and life expectancy clocks based on machine learning analysis of mouse frailty | bioRxiv

Health Hacker Australia > The Science > Ageing, Longevity and disease. > Age and life expectancy clocks based on machine learning analysis of mouse frailty | bioRxiv

“The identification of genes and interventions that slow or reverse aging is hampered by the lack of non-invasive metrics that can predict life expectancy of pre-clinical models. Frailty Indices (FIs) in mice are composite measures of health that are cost-effective and non-invasive, but whether they can accurately predict health and lifespan is not known. Here, mouse FIs were scored longitudinally until death and machine learning was employed to develop two clocks. ”

https://www.biorxiv.org/content/10.1101/2019.12.20.884452v1

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