Tag: Alzheimers

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Medium Chain Triglycerides induce mild ketosis and may improve cognition in Alzheimer’s disease. A systematic review and meta-analysis of human studies – ScienceDirect

Medium Chain Triglycerides induce mild ketosis and may improve cognition in Alzheimer’s disease. A systematic review and meta-analysis of human studies – ScienceDirect

Posted on by Nathan

Highlights
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From meta-analysis of RCTs in Alzheimer’s disease and Mild Cognitive Impairment, oral Medium Chain Triglycerides administration induced mild peripheral ketosis

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From meta-analysis of RCTs in Alzheimer’s disease and Mild Cognitive Impairment, oral Medium Chain Triglycerides administration improved cognition on a combined scale of ADAS-Cog and MMSE.

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Risk of bias of existing studies of RCTs in Alzheimer’s disease and Mild Cognitive Impairment necessitates future trials.

https://www.sciencedirect.com/science/article/pii/S156816371930131X

Potassium channels in the neuronal homeostasis and neurodegenerative pathways underlying Alzheimer’s Disease: an update – ScienceDirect

Potassium channels in the neuronal homeostasis and neurodegenerative pathways underlying Alzheimer’s Disease: an update – ScienceDirect

Posted on by Nathan

Highlights

•Potassium (K+) channels are key regulators of cell excitability in several tissues.

•A dysregulation of K+ channels is associated with Alzheimer’s disease (AD).

•The role of K+ channels in AD is not completely elucidated.

•Understanding their functions will be helpful for clarifying AD pathogenesis.

•Modulating K+ channel expression should be useful for developing novel drugs.

Potassium channels in the neuronal homeostasis and neurodegenerative pathways underlying Alzheimer’s Disease: an update – ScienceDirect