“Adequate dietary intake of essential metals such as zinc is important for maintaining homeostasis. Abnormal zinc intake in Caenorhabditis elegans has been shown to increase or decrease normal lifespan by influencing the insulin/IGF‐1 pathway. Distribution of zinc is achieved by a family of highly conserved zinc transport proteins (ZIPT in C. elegans). This study investigated the role of the zipt family of genes and show that depletion of individual zipt genes results in a decreased lifespan”

https://febs.onlinelibrary.wiley.com/doi/abs/10.1002/1873-3468.13725