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Mitochondria—hubs for regulating cellular biochemistry: emerging concepts and networks | Open Biology

Mitochondria—hubs for regulating cellular biochemistry: emerging concepts and networks | Open Biology

Posted on by Nathan

Mitochondria are iconic structures in biochemistry and cell biology, traditionally referred to as the powerhouse of the cell due to a central role in energy production. However, modern-day mitochondria are recognized as key players in eukaryotic cell biology and are known to regulate crucial cellular processes, including calcium signalling, cell metabolism and cell death, to name a few. In this review, we will discuss foundational knowledge in mitochondrial biology and provide snapshots of recent advances that showcase how mitochondrial function regulates other cellular responses.

https://royalsocietypublishing.org/doi/full/10.1098/rsob.190126?utm_source=researcher-app&utm_medium=researcherad&utm_campaign=DVaughan_Promotedpaper_190126&utm_content=Paper

Mitochondria—hubs for regulating cellular biochemistry: emerging concepts and networks | Open Biology

Mitochondria—hubs for regulating cellular biochemistry: emerging concepts and networks | Open Biology

Posted on by Nathan

“Mitochondria are iconic structures in biochemistry and cell biology, traditionally referred to as the powerhouse of the cell due to a central role in energy production. However, modern-day mitochondria are recognized as key players in eukaryotic cell biology and are known to regulate crucial cellular processes, including calcium signalling, cell metabolism and cell death, to name a few. In this review, we will discuss foundational knowledge in mitochondrial biology and provide snapshots of recent advances that showcase how mitochondrial function regulates other cellular responses.”

https://royalsocietypublishing.org/doi/full/10.1098/rsob.190126?utm_source=researcher-app&utm_medium=researcherad&utm_campaign=DVaughan_Promotedpaper_190126&utm_content=Paper

Probiotic bacteria as modulators of cellular senescence: emerging concepts and opportunities

Probiotic bacteria as modulators of cellular senescence: emerging concepts and opportunities

Posted on by Nathan

“Probiotic bacteria are increasingly gaining importance in human nutrition owing to their multifaceted health beneficial effects. Studies have also shown that probiotic supplementation is useful in mitigating age-associated oxi-inflammatory stress, immunosenescence, and gut dysbiosis thereby promoting health and longevity. However, our current understanding of the process of aging suggests a strong interrelationship between the accumulation of senescent cells and the development of aging phenotype, including the predisposition to age-related disorders. The present review studies the documented pro-longevity effects of probiotics and highlights how these beneficial attributes of probiotics could be related to the mitigation of cellular senescence. ”

https://www.tandfonline.com/doi/full/10.1080/19490976.2019.1697148?af=R&utm_source=researcher_app&utm_medium=referral&utm_campaign=RESR_MRKT_Researcher_inbound