Tag: ageing

Health Hacker Australia > ageing
The State of Ageing in 2019: Adding life to our years | Centre for Ageing Better

The State of Ageing in 2019: Adding life to our years | Centre for Ageing Better

Posted on by Nathan

How prepared is society for our longer lives? Our new report, ‘The State of Ageing in 2019’, uses publicly available data to give a snapshot of what life is like for people aged 65 and older today. It also investigates the prospects for people currently in their 50s and 60s looking across four crucial areas: work and finances, housing, health and communities.

The State of Ageing in 2019: Adding life to our years

https://www.ageing-better.org.uk/publications/state-of-ageing-2019

Growth Hormone DHEA Metformin In Aging Clinical Study

Growth Hormone DHEA Metformin In Aging Clinical Study

Posted on by Nathan

“A new clinical trial found that a combination of Growth Hormone, DHEA & Metformin helped to restore the size of the thymus gland and reverse biological age (epigenetic age via the GrimAge test).”

➢ Link to study:

Fahy, G. M., Brooke, R. T., Watson, J. P., Good, Z., Vasanawala, S. S., Maecker, H., et al. (2019). Reversal of epigenetic aging and immunosenescent trends in humans. Aging Cell, 18(6), 421–12. http://doi.org/10.1111/acel.13028

https://highintensityhealth.com/growth-hormone-dhea-metformin-in-aging-clinical-study/

NMN – Nicotinimide Mononucleotide

NMN – Nicotinimide Mononucleotide

Posted on by Nathan
MIB-626, the NAD+ precursor that’s superior to NMN
A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration
The elusive NMN transporter is found | Nature Metabolism
David Sinclair – Can NMN Reverse Aging? – YouTube
Effect of “Nicotinamide Mononucleotide” (NMN) on Cardiometabolic Function – Full Text View – ClinicalTrials.gov
A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration
Metformin

Metformin

Posted on by Nathan
This cheap pill might help you live a longer, healthier life
Metformin as Anti-Aging Therapy: Is It for Everyone?: Trends in Endocrinology & Metabolism
Full title: High glucose protects mesenchymal stem cells from metformin-induced apoptosis through the AMPK-mediated mTOR pathway | Scientific Reports
Diabetes drug has unexpected, broad implications for healthy aging
Mitochondrial targets of metformin-Are they physiologically relevant? – PubMed – NCBI
Host-Microbe-Drug-Nutrient Screen Identifies Bacterial Effectors of Metformin Therapy: Cell
Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus | Nature Reviews Endocrinology
H19 lncRNA alters methylation and expression of Hnf4α in the liver of metformin-exposed fetuses | Cell Death & Disease
Pro-neurocognitive and Anti-sarcopenic benefits of one-year Metformin therapy in ovariectomized aged mice. – PubMed – NCBI

Risks: this risk is low (less than 10 cases for 100,000 patient years), but the risk of metformin-induced lactic acidosis (MALA) increases in certain situations where both the plasma levels of metformin are increased and lactate clearance is impaired.[6]