Category: depression and anxiety

Health Hacker Australia > The Science > Brain Health > depression and anxiety
The serotonin theory of depression: a systematic umbrella review of the evidence | Molecular Psychiatry

The serotonin theory of depression: a systematic umbrella review of the evidence | Molecular Psychiatry

The main areas of serotonin research provide no consistent evidence of there being an association between serotonin and depression, and no support for the hypothesis that depression is caused by lowered serotonin activity or concentrations. Some evidence was consistent with the possibility that long-term antidepressant use reduces serotonin concentration.

https://www.nature.com/articles/s41380-022-01661-0

Consumption of Omega-3 and Maintenance and Incidence of Depressive Episodes: The ELSA-Brasil Study

Consumption of Omega-3 and Maintenance and Incidence of Depressive Episodes: The ELSA-Brasil Study

Depression affects 264 million persons in the world, accounting for some 4.3% of the global burden of disease. Current studies indicate that the decrease in the consumption of omega-3 food sources is associated with the increasing incidence of depression. The study aims to assess the association between the consumption of omega-3 and the maintenance and incidence of depressive episodes in adults (39–64 years) and elderly adults (>65 years). This was a longitudinal study using data from the baseline and first follow-up wave of the Longitudinal Study of Adult Health (ELSA-Brasil). Depressive episodes were obtained with the Clinical Interview Schedule Revised (CIS-R), and food consumption was measured with the Food Frequency Questionnaire (FFQ). Logistic regression was used to analyze associations between the consumption of omega-3 and depressive episodes. Fatty acids from the omega-3 family showed a protective effect against the maintenance of depressive episodes. In relation to incidence, the estimates suggest that the higher the consumption of omega-3 acids, the lower the risk of developing depressive episodes, and significant associations were found between the consumption of omega-3 and alpha-linolenic acid. Dietary consumption of omega-3, DHA, EPA, DPA, and alpha linolenic fatty acids may have a protective effect against the maintenance and incidence of depressive episodes.

Consumption of Omega-3 and Maintenance and Incidence of Depressive Episodes: The ELSA-Brasil Study https://link.researcher-app.com/EhnP – via Researcher (@ResearcherApp)

Psilocybin microdosers demonstrate greater observed improvements in mood and mental health at one month relative to non-microdosing controls | Scientific Reports

Psilocybin microdosers demonstrate greater observed improvements in mood and mental health at one month relative to non-microdosing controls | Scientific Reports

https://www.nature.com/articles/s41598-022-14512-3

‘Psychedelics renaissance’: new wave of research puts hallucinogenics forward to treat mental health | Mental health | The Guardian

‘Psychedelics renaissance’: new wave of research puts hallucinogenics forward to treat mental health | Mental health | The Guardian

https://www.theguardian.com/society/2021/sep/26/psychedelics-renaissance-new-wave-of-research-puts-hallucinogenics-forward-to-treat-mental-health?CMP=Share_iOSApp_Other